Fructose

Fructose

SCHEMBL3036243

CC(C)=O.CC(C)=O.O=C(CO)[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.52
TSHR P16473 1/20 0.52
PDE4A P27815 1/20 0.46
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fructose SCHEMBL28298046 1.00 CYP2C9 (0.52) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL11432055 1.00 CYP2C9 (0.52) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL28155729 1.00 CYP2C9 (0.52) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL10835862 1.00 CYP2C9 (0.52) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL2638706 1.00 CYP2C9 (0.52) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL7162293 0.93 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL27690289 0.93 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL27668222 0.93 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL6244358 0.93 CYP2C9 (0.54) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL9788519 0.93 CYP2C9 (0.54) CYP2C9TSHRPDE4ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1018645-B METHOD OF PRODUCING DIACETONE SORBOSE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-10-14 CN claimed
US-H708-H SORBOSE; ACETONE; CATALYST OF IODINE, SULFURIC ACID, PERCHLORIC ACID; ZEOLITE DEHYDRATION; CONTINUOUS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-11-07 US claimed
CN-87103553-A Produce the method for diacetone sorbose 1988-03-09 CN claimed
US-4414401-A Process for separating and recovering metal catalysts MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-08 US claimed
JP-63045292-A None JP disclosed
US-20230056533-A1 Radial Glia and Astrocyte Differentiation From Human Pluripotent Stem Cells THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2023-02-23 US disclosed
EP-4107255-A1 RADIAL GLIA AND ASTROCYTE DIFFERENTIATION FROM HUMAN PLURIPOTENT STEM CELLS The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) 2022-12-28 EP disclosed
US-8383837-B2 Reaction with a gold catalyst DSM IP ASSETS B.V. (NL) 2013-02-26 US disclosed
US-20100217017-A1 NOVEL REACTION WITH A GOLD CATALYST DSM IP ASSETS B.V. (NL) 2010-08-26 US disclosed
EP-2155650-A2 NOVEL REACTION WITH A GOLD CATALYST DSM IP Assets B.V. (NL) 2010-02-24 EP disclosed
WO-2008148549-A2 NOVEL REACTION WITH A GOLD CATALYST DSM IP ASSETS B.V. (NL) 2008-12-11 WO disclosed
CN-1966703-A Process for one-step fermentation production of gulonic acid (VC precursor) from glucose GE ZHONGLIANG (CN) 2007-05-23 CN disclosed
CN-87103553-A Produce the method for diacetone sorbose 1988-03-09 CN disclosed
CN-87103553-A Produce the method for diacetone sorbose 1988-03-09 CN disclosed
JP-S6345292-A PRODUCTION OF DIACETONE SORBOSE TAKEDA CHEM IND LTD 1988-02-26 JP disclosed
EP-0231354-A1 PRODUCTION OF A VITAMIN C PRECURSOR USING GENETICALLY MODIFIED ORGANISMS. BIOGEN NV (NL) 1987-08-12 EP disclosed
WO-1987000863-A1 PRODUCTION OF A VITAMIN C PRECURSOR USING GENETICALLY MODIFIED ORGANISMS BIOGEN N.V. (AN) 1987-02-12 WO disclosed
EP-0113835-A1 Method for the purification of diaceton sorbose MERCK PATENT GmbH (DE) 1984-07-25 EP disclosed
US-4414401-A Process for separating and recovering metal catalysts MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-08 US disclosed
US-4414401-A Process for separating and recovering metal catalysts MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217017-A1 NOVEL REACTION WITH A GOLD CATALYST ADH1C, ADH1A, ADH5 CYP2C9 981/4885TSHR 1401/4885PDE4A 4210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.