Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13507957 | 0.83 | PRCP (0.53) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL8030423 | 0.78 | SRD5A1 (0.43) | DRD1DRD2DRD4MAOA | |
| SCHEMBL8032022 | 0.78 | HTR2A (0.43) | PRCPDRD2MAOA | |
| SCHEMBL8023492 | 0.76 | PRCP (0.61) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL811761 | 0.76 | PRCP (0.61) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL8021507 | 0.76 | PRCP (0.61) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL8030400 | 0.75 | MEN1 (0.42) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL29445708 | 0.74 | PRCP (0.59) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL4757289 | 0.74 | PRCP (0.59) | PRCPDRD1DRD2DRD4DRD5 | |
| SCHEMBL652030 | 0.74 | PRCP (0.59) | PRCPDRD1DRD2DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |