SCHEMBL8025867

SCHEMBL8025867

CCC[C@H]1CC[C@H](c2ccc(Cl)cc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.59
DRD2 P14416 1/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
SLC6A3 Q01959 1/20 0.49
ESR2 Q92731 3/20 0.47
LSS P48449 1/20 0.43
IDO1 P14902 1/20 0.42
SLC2A1 P11166 1/20 0.42
HTR3A P46098 1/20 0.42
ESR1 P03372 1/20 0.42
CYP3A4 P08684 1/20 0.42
SRD5A1 P18405 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260852 1.00 CYP2C9 (0.59) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8398937 0.95 CYP2C9 (0.55) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL17552974 0.95 CYP2C9 (0.55) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL7510559 0.95 CYP2C9 (0.55) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8398929 0.95 CYP2C9 (0.55) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8448301 0.93 CYP2C9 (0.54) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8448306 0.93 CYP2C9 (0.54) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8448309 0.93 CYP2C9 (0.54) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8377290 0.92 CYP2C9 (0.52) CYP2C9DRD2MEN1KMT2AALDH1A1
SCHEMBL8377293 0.92 CYP2C9 (0.52) CYP2C9DRD2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58079938-A None JP disclosed
JP-8073857-A None JP disclosed
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
EP-0679707-B1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 1999-06-16 EP disclosed
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0688754-B1 DICYCLOHEXYLETHYLENE DERIVATIVE CHISSO CORP (JP) 1998-10-07 EP disclosed
US-5720899-A Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-02-24 US disclosed
US-5653911-A Liquid crystalline compound liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1997-08-05 US disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0471831-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 1996-08-14 EP disclosed
JP-H0873857-A LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORP 1996-03-19 JP disclosed
EP-0688754-A1 DICYCLOHEXYLETHYLENE DERIVATIVE CHISSO CORPORATION (JP) 1995-12-27 EP disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed
US-5456860-A Containing liquid crystal mixture based on dielectrically positive compounds which contain polar end group with specified lipophilicity parameter MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-10-10 US disclosed
US-5389289-A Chemical and heat resistance MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-14 US disclosed
EP-0450354-A2 Matrix-liquid crystal display MERCK PATENT GmbH (DE) 1991-10-09 EP disclosed
EP-0074608-B1 LIQUID CRYSTAL HALOGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION, DIELECTRIC AND DECTROOPTICAL DISPLAY ELEMENT CONTAINING THEM MERCK PATENT GmbH (DE) 1985-07-03 EP disclosed
US-4490305-A Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-12-25 US disclosed
JP-S5879938-A 4-(TRANS-4'-ALKYLCYCLOHEXYL)-CHLOROBENZENE ASAHI GLASS CO LTD 1983-05-13 JP disclosed
EP-0074608-A2 Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them MERCK PATENT GmbH (DE) 1983-03-23 EP disclosed