Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448309 | 1.00 | CYP2C9 (0.54) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8448301 | 1.00 | CYP2C9 (0.54) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL17552974 | 0.98 | CYP2C9 (0.55) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL260852 | 0.93 | CYP2C9 (0.59) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8025867 | 0.93 | CYP2C9 (0.59) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8450938 | 0.91 | DRD2 (0.49) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8450943 | 0.91 | DRD2 (0.49) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8450939 | 0.91 | DRD2 (0.49) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8453164 | 0.90 | DRD2 (0.47) | CYP2C9DRD2ALDH1A1LMNAMAPT | |
| SCHEMBL8453170 | 0.90 | DRD2 (0.47) | CYP2C9DRD2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |