Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401140 | 0.89 | MAPKAPK2 (0.61) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL2707877 | 0.88 | MAPKAPK2 (0.62) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL6242196 | 0.84 | MAPKAPK2 (0.58) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL8025885 | 0.83 | MAPKAPK2 (0.56) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL28468251 | 0.79 | MAPKAPK2 (0.52) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL30618016 | 0.79 | MAPT (0.55) | MAPKAPK2MAPTTP53ALDH1A1ABCG2 | |
| SCHEMBL15241465 | 0.79 | MAPT (0.55) | MAPKAPK2MAPTTP53ALDH1A1ABCG2 | |
| SCHEMBL28468254 | 0.78 | KIF11 (0.52) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL30196665 | 0.78 | BCHE (0.54) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 | |
| SCHEMBL7850958 | 0.78 | MAPKAPK2 (0.53) | MAPKAPK2MAPTTP53SIRT1MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |