Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 19/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026714 | 0.92 | SLC10A2 (0.48) | SLC10A2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL21586090 | 0.88 | SLC10A2 (0.49) | SLC10A2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL6309108 | 0.88 | SLC10A2 (0.43) | SLC10A2 | |
| SCHEMBL5226757 | 0.87 | SLC10A2 (0.42) | SLC10A2 | |
| SCHEMBL30728278 | 0.87 | SLC10A2 (0.47) | SLC10A2 | |
| SCHEMBL8015441 | 0.87 | SLC10A2 (0.48) | SLC10A2 | |
| SCHEMBL6307088 | 0.86 | SLC10A2 (0.46) | SLC10A2 | |
| SCHEMBL5226762 | 0.85 | SLC10A2 (0.38) | SLC10A2 | |
| SCHEMBL8024294 | 0.85 | SLC10A2 (0.42) | SLC10A2 | |
| SCHEMBL30728313 | 0.85 | SLC10A2 (0.40) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792268-B1 | HYPOLIPIDEMIC BENZOTHIAZEPINES | WELLCOME FOUND (GB) | 2000-02-23 | — | — | EP | claimed |
| US-5998400-A | Hypolipidemic benzothiazepines | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0792268-B1 | HYPOLIPIDEMIC BENZOTHIAZEPINES | WELLCOME FOUND (GB) | 2000-02-23 | — | — | EP | disclosed |
| US-5998400-A | Hypolipidemic benzothiazepines | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1996016051-A1 | HYPOLIPIDEMIC BENZOTHIAZEPINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-05-30 | — | — | WO | disclosed |