Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.60 |
| ▸ | RARB | P10826 | 10/20 | 0.60 |
| ▸ | RARG | P13631 | 9/20 | 0.60 |
| ▸ | RXRB | P28702 | 7/20 | 0.60 |
| ▸ | RARA | P10276 | 6/20 | 0.60 |
| ▸ | RXRG | P48443 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421758 | 0.91 | RXRA (0.72) | RXRARARBRARGRXRBRARA | |
| SCHEMBL8026151 | 0.89 | RXRA (0.78) | RXRARARBRARGRXRBRARA | |
| SCHEMBL8026112 | 0.87 | RARB (0.58) | RXRARARBRARGRXRBRARA | |
| SCHEMBL7896511 | 0.82 | RXRA (0.63) | RXRARARBRARGRXRBRARA | |
| SCHEMBL9746786 | 0.82 | RARB (0.74) | RXRARARBRARGRXRBRARA | |
| SCHEMBL8026092 | 0.81 | RARB (0.61) | RXRARARBRARGRARACYP3A4 | |
| SCHEMBL2788640 | 0.79 | CYP3A4 (0.70) | RXRARARBRARGRXRBRARA | |
| SCHEMBL6814372 | 0.79 | RXRA (0.49) | RXRARARBRARGRXRBRARA | |
| SCHEMBL9319204 | 0.77 | CYP3A4 (0.67) | RXRARARBRARGRXRBRARA | |
| SCHEMBL7422927 | 0.77 | RXRA (0.70) | RXRARARBRARGRXRBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |