Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 5/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348725 | 0.98 | GNAO1 (0.47) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL19634573 | 0.94 | GNAO1 (0.51) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL7043670 | 0.94 | HRH2 (0.50) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL19634497 | 0.93 | GNAO1 (0.54) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL20332759 | 0.93 | GNAO1 (0.54) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL23471205 | 0.93 | GNAO1 (0.54) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| Bromide SCHEMBL8520315 | 0.91 | GNAO1 (0.53) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL8392333 | 0.89 | HRH2 (0.40) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL26940881 | 0.89 | GNAO1 (0.50) | GNAO1GNAI3GNAI1HRH2HRH1 | |
| SCHEMBL21348420 | 0.89 | CXCR4 (0.46) | GNAO1GNAI3GNAI1HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-0527051-B1 | Quinophthalone dyes, ink composition and transfer sheet containing them | MITSUI CHEMICALS INC (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5387686-A | Sublimable, yellow quinoline derivatives; storage stable; heat light, chemical resistant | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-07 | — | — | US | disclosed |
| US-5296445-A | Quinoline dyes | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0527051-A1 | Quinophthalone dyes, ink composition and transfer sheet containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-10 | — | — | EP | disclosed |