Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.67 |
| ▸ | F10 | P00742 | 6/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 4/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8028460 | 0.99 | F2 (0.66) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8027015 | 0.98 | F2 (0.65) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6638105 | 0.90 | F2 (0.57) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6633749 | 0.86 | F2 (0.51) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8029893 | 0.84 | F2 (0.46) | F2 | |
| SCHEMBL8027045 | 0.83 | F2 (0.45) | F2 | |
| Hydrochloric Acid SCHEMBL8029612 | 0.82 | F2 (0.77) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8166575 | 0.80 | F2 (1.00) | F2KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL8016790 | 0.79 | F2 (0.98) | F2KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL8016175 | 0.78 | F2 (0.73) | F2KLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | claimed |
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |