Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8612137 | 0.99 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL8022895 | 0.92 | OPRK1 (0.64) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL19253141 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL4663680 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL4663363 | 0.91 | OPRK1 (0.60) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL8615115 | 0.91 | OPRK1 (0.62) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL4665394 | 0.91 | OPRK1 (0.65) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL4663858 | 0.90 | SLC6A2 (0.53) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL4665364 | 0.89 | OPRK1 (0.58) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 | |
| SCHEMBL8024119 | 0.88 | OPRK1 (0.47) | OPRK1SLC6A2SLC6A4OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |