Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 17/20 | 0.80 |
| ▸ | ACE | P12821 | 13/20 | 0.80 |
| ▸ | CPA1 | P15085 | 4/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026891 | 1.00 | MME (0.80) | MMEACECPA1ACE2TP53 | |
| SCHEMBL8448663 | 1.00 | MME (0.80) | MMEACECPA1ACE2TP53 | |
| SCHEMBL8030323 | 0.95 | MME (0.71) | MMEACETP53 | |
| SCHEMBL8030327 | 0.95 | MME (0.71) | MMEACETP53 | |
| SCHEMBL8451813 | 0.95 | MME (0.71) | MMEACETP53 | |
| SCHEMBL8027335 | 0.93 | MME (0.82) | MMEACECPA1ACE2 | |
| SCHEMBL8027331 | 0.93 | MME (0.82) | MMEACECPA1ACE2 | |
| SCHEMBL8028762 | 0.93 | MME (0.70) | MMEACECPA1ACE2 | |
| SCHEMBL8447391 | 0.93 | MME (0.70) | MMEACECPA1ACE2 | |
| SCHEMBL27446784 | 0.91 | MME (0.66) | MMEACETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |