Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.70 |
| ▸ | ACE | P12821 | 13/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447391 | 1.00 | MME (0.70) | MMEACEHDAC1HDAC6CPA1 | |
| SCHEMBL8018081 | 0.94 | MME (0.71) | MMEACEHDAC1HDAC6CPA1 | |
| SCHEMBL8027565 | 0.93 | MME (0.81) | MMEACECPA1ACE2TACR1 | |
| SCHEMBL8447827 | 0.93 | MME (0.81) | MMEACECPA1ACE2TACR1 | |
| SCHEMBL8026896 | 0.93 | MME (0.80) | MMEACECPA1ACE2 | |
| SCHEMBL8448663 | 0.93 | MME (0.80) | MMEACECPA1ACE2 | |
| SCHEMBL8026891 | 0.93 | MME (0.80) | MMEACECPA1ACE2 | |
| SCHEMBL8027344 | 0.91 | MME (0.85) | MMEACECPA1ACE2 | |
| SCHEMBL8027132 | 0.90 | MME (0.68) | MMEACEHDAC1HDAC6 | |
| SCHEMBL27440145 | 0.89 | MME (0.57) | MMEACEHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |