Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.79 |
| ▸ | ACE | P12821 | 13/20 | 0.79 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027560 | 0.94 | MME (0.80) | MMEACECTSBCTSSCTSK | |
| SCHEMBL8027132 | 0.93 | MME (0.68) | MMEACECTSBCTSSCTSK | |
| SCHEMBL8017233 | 0.89 | MME (0.68) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8447827 | 0.89 | MME (0.81) | MMEACECTSBCTSSCPA1 | |
| SCHEMBL8027565 | 0.89 | MME (0.81) | MMEACECTSBCTSSCPA1 | |
| SCHEMBL8027115 | 0.89 | MME (0.77) | MMEACECTSSCTSKACE2 | |
| SCHEMBL6440665 | 0.88 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8027151 | 0.88 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8033744 | 0.88 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8032890 | 0.88 | MME (1.00) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |