Biphenyl

Biphenyl

SCHEMBL8027156

OC1CCC(O)CC1.[Zn].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ADORA3 P0DMS8 2/20 0.40
ESR2 Q92731 1/20 0.39
ADORA2A P29274 2/20 0.39
ADORA2B P29275 2/20 0.39
ADORA1 P30542 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MGLL Q99685 1/20 0.39
KCNA3 P22001 1/20 0.38
KDM1A O60341 2/20 0.38
KMO O15229 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28893342 0.94 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1RAB9ANPC1
Biphenyl SCHEMBL28053113 0.89 ALDH1A1 (0.50) ALDH1A1MMP3BCL2L1RAB9ANPC1
SCHEMBL7265967 0.82 NPC1 (0.65) ALDH1A1MMP3RAB9ANPC1SMN1; SMN2
Biphenyl SCHEMBL28384213 0.78 ALDH1A1 (0.50) ALDH1A1MMP3BCL2L1MEN1KMT2A
Biphenyl SCHEMBL547965 0.74 ALDH1A1 (0.90) ALDH1A1MMP3BCL2L1RAB9ANPC1
Biphenyl SCHEMBL21647236 0.74 ALDH1A1 (0.90) ALDH1A1MMP3BCL2L1RAB9ANPC1
Biphenyl SCHEMBL28098924 0.74 ALDH1A1 (0.90) ALDH1A1MMP3BCL2L1RAB9ANPC1
Catechol SCHEMBL16584581 0.74 ALDH1A1 (0.59) ALDH1A1BCL2L1RAB9ANPC1MEN1
SCHEMBL557667 0.74 ESR2 (0.64) ALDH1A1SMN1; SMN2ESR2CYP1A2
Biphenyl SCHEMBL27760195 0.72 ALDH1A1 (0.69) ALDH1A1MMP3BCL2L1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136946-A ESTER INTERCHANGE WITH HEATING IN PRESENCE OF BASIC OXIDE CATALYST FUJI XEROX CO., LTD. (JP) 2000-10-24 US disclosed