Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ACACB | O00763 | 7/20 | 0.45 |
| ▸ | ACACA | Q13085 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1580718 | 0.81 | KMT2A (0.57) | KMT2AACACBACACACTSSCTSK | |
| SCHEMBL3816616 | 0.81 | KMT2A (0.56) | KMT2AACACBACACACTSSCTSK | |
| SCHEMBL3942686 | 0.81 | KMT2A (0.56) | KMT2AACACBACACACTSSCTSK | |
| SCHEMBL4377073 | 0.81 | KMT2A (0.56) | KMT2AACACBACACACTSSCTSK | |
| SCHEMBL190838 | 0.81 | KMT2A (0.56) | KMT2AACACBACACACTSSCTSK | |
| SCHEMBL21242136 | 0.81 | CA2 (0.38) | — | |
| SCHEMBL8027222 | 0.81 | KMT2A (0.47) | KMT2AACACBACACAATMCTSS | |
| SCHEMBL30524563 | 0.80 | CA2 (0.37) | — | |
| SCHEMBL7818584 | 0.79 | KMT2A (0.52) | KMT2AACACBACACACTSSCTSK | |
| SCHEMBL20855847 | 0.79 | KMT2A (0.52) | KMT2AACACBACACACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763016-B1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS | AXYS PHARM INC (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5656660-A | AMINE OR GUANIDINE GROUP-CONTAINING TRYPTASE INHIBITOR | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |