Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | SHBG | P04278 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343128 | 0.98 | MAPT (0.79) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL21067996 | 0.91 | MAPT (0.84) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL11121455 | 0.89 | MAPT (0.75) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL604525 | 0.88 | LMNA (0.73) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL17419490 | 0.87 | MAPT (0.98) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL23752494 | 0.87 | MAPT (0.78) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL17419472 | 0.87 | MAPT (0.78) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL14568852 | 0.87 | MAPT (1.00) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL11593159 | 0.87 | MAPT (1.00) | MAPTLMNASERPINA6ALDH1A1THRB | |
| SCHEMBL11351978 | 0.87 | MAPT (1.00) | MAPTLMNASERPINA6ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| EP-0665009-B1 | CRYSTALLINE CONDITION DISLOCATING METHOD | NIPPON SHINYAKU CO LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0665009-A1 | CRYSTALLINE CONDITION DISLOCATING METHOD | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-08-02 | — | — | EP | disclosed |