SCHEMBL8027520

SCHEMBL8027520

CCCC/C(C(=O)O)=C(\C(=O)OO)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.41
FNTB P49356 2/20 0.41
THRB P10828 1/20 0.41
PGGT1B P53609 1/20 0.41
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.36
CES1 P23141 2/20 0.34
CES2 O00748 1/20 0.34
AKR1B1 P15121 1/20 0.32
GPR84 Q9NQS5 7/20 0.31
PPARG P37231 6/20 0.31
PPARD Q03181 6/20 0.31
PPARA Q07869 6/20 0.31
HDAC11 Q96DB2 5/20 0.31
TSHR P16473 4/20 0.31
TLR2 O60603 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
FABP4 P15090 2/20 0.31
PTPN1 P18031 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8027526 1.00 FNTA (0.41) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL8027522 0.89 ALDH1A1 (0.39) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL9720981 0.83 FNTA (0.47) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL9709237 0.83 FNTA (0.47) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL28364867 0.80 FNTA (0.47) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL10592909 0.75 CES1 (0.48) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL9579507 0.73 FNTA (0.58) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL180490 0.72 FNTA (0.60) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL555771 0.72 FNTA (0.60) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL180491 0.72 FNTA (0.60) FNTAFNTBTHRBPGGT1BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156855-A Production of branched polymers THE DOW CHEMICAL COMPANY (US) 2000-12-05 US disclosed
EP-0912615-B1 PRODUCTION OF BRANCHED POLYMERS DOW CHEMICAL CO (US) 2000-08-30 EP disclosed
EP-0862586-B1 A PROCESS FOR PREPARING A BRANCHED POLYMER FROM A VINYL AROMATIC MONOMER DOW CHEMICAL CO (US) 2000-08-23 EP disclosed
EP-0912615-A1 PRODUCTION OF BRANCHED POLYMERS THE DOW CHEMICAL COMPANY (US) 1999-05-06 EP disclosed
EP-0862586-A2 A PROCESS FOR PREPARING A BRANCHED POLYMER FROM A VINYL AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1998-09-09 EP disclosed
WO-1998003556-A1 PRODUCTION OF BRANCHED POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-01-29 WO disclosed
US-5663252-A FREE RADICAL POLYMERIZATION WITH UNSATURATED PEROXYCARBOXYLIC ACIDS AND STYRENE THE DOW CHEMICAL COMPANY (US) 1997-09-02 US disclosed
WO-1997020862-A2 A PROCESS FOR PREPARING A BRANCHED POLYMER FROM A VINYL AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1997-06-12 WO disclosed
US-5473031-A Polymerizing styrene with two other unsaturated compounds having different but reactive groups THE DOW CHEMICAL COMPANY (US) 1995-12-05 US disclosed