Propionic Acid

Propionic Acid

SCHEMBL8027701

C=C(C)C(=O)OCC.CCC(=O)O.CNC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
EGLN1 Q9GZT9 1/20 0.46
TSHR P16473 4/20 0.44
ALDH1A1 P00352 7/20 0.43
CYP2D6 P10635 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
MAPT P10636 2/20 0.40
FFAR3 O14843 1/20 0.40
GLO1 Q04760 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SOAT1 P35610 1/20 0.38
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8023904 0.92 THRB (0.53) THRBEGLN1TSHRALDH1A1CYP2D6
Dimethylamine SCHEMBL321116 0.92 THRB (0.57) THRBEGLN1TSHRALDH1A1CYP2D6
Methacrylic Acid SCHEMBL17360628 0.90 THRB (0.52) THRBEGLN1TSHRALDH1A1CYP2D6
Dimethylamine SCHEMBL7516850 0.90 THRB (0.55) THRBEGLN1TSHRALDH1A1CYP2D6
Dimethylamine SCHEMBL2982086 0.90 THRB (0.55) THRBEGLN1TSHRALDH1A1CYP2D6
Dimethylamine SCHEMBL8665783 0.88 THRB (0.53) THRBEGLN1TSHRALDH1A1CYP2D6
Malonic Acid SCHEMBL3868425 0.88 THRB (0.53) THRBEGLN1TSHRALDH1A1CYP2D6
Acetic Acid SCHEMBL28298395 0.85 THRB (0.59) THRBEGLN1TSHRALDH1A1CYP2D6
Bicarbonate SCHEMBL10996730 0.85 THRB (0.59) THRBEGLN1TSHRALDH1A1CYP2D6
SCHEMBL19409375 0.85 THRB (0.64) THRBEGLN1TSHRALDH1A1MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760136-A FORMING AN ADDITION-CONDENSATION COPOLYMER BY POLYMERIZING AN AZO-CONTAINING POLYSILOXANE AND AN UNSATURATED MONOMER; CATIONIC AND NONIONIC POLYMERS; POLYAMPHOLYTES; COATINGS; ADHESIVES; PAINTS; HAIR COSMETICS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-02 US claimed
EP-0779318-B1 Silicon-containing block copolymer WAKO PURE CHEMICAL INDUSTIES L (JP) 2000-02-16 EP disclosed
EP-0779318-A1 Silicon-containing block copolymer Wako Pure Chemical Industries, Ltd. (JP) 1997-06-18 EP disclosed