Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027242 | 0.93 | CCR5 (0.44) | CCR5 | |
| SCHEMBL8024025 | 0.92 | CCR5 (0.50) | CCR5 | |
| SCHEMBL8026049 | 0.89 | CCR5 (0.48) | CCR5 | |
| SCHEMBL8029411 | 0.89 | CCR5 (0.48) | CCR5 | |
| SCHEMBL8029446 | 0.88 | CCR5 (0.50) | CCR5 | |
| SCHEMBL8025375 | 0.83 | CCR5 (0.55) | CCR5 | |
| SCHEMBL7871142 | 0.82 | CCR5 (0.51) | CCR5 | |
| SCHEMBL7871145 | 0.82 | CCR5 (0.51) | CCR5 | |
| SCHEMBL8013477 | 0.82 | CCR5 (0.44) | CCR5 | |
| SCHEMBL7863007 | 0.82 | CCR5 (0.48) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000051608-A1 | 3-THIENYL AND 3-FURANYL PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |