Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943625 | 0.78 | BACE1 (0.39) | MAOB | |
| SCHEMBL9863913 | 0.73 | CHRNB4 (0.41) | ALOX5NOTUMNISCHMAOB | |
| SCHEMBL28415810 | 0.73 | HTR2C (0.36) | MAOB | |
| SCHEMBL5791186 | 0.72 | BRD4 (0.41) | MAOBCYP1A2 | |
| SCHEMBL8607855 | 0.71 | BACE1 (0.50) | SLC6A3 | |
| SCHEMBL11502520 | 0.71 | MAPT (0.41) | GSTP1HDAC4HDAC2HDAC8MAOB | |
| SCHEMBL11146097 | 0.70 | TDP1 (0.54) | GSTP1HDAC2SLC6A2SLC6A3ESR1 | |
| SCHEMBL11133453 | 0.70 | BACE1 (0.41) | MAOBCYP1A2 | |
| SCHEMBL8026608 | 0.70 | PTPN1 (0.46) | NISCHMAOB | |
| SCHEMBL4269525 | 0.70 | GSTP1 (0.42) | GSTP1HDAC4HDAC2HDAC8SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064908-A1 | N-TRI OR DI-ALKYLSILYL( PERFLUOROAL KANESULPHONYL) IMIDE DERIVATIVES, PREPARATION AND USE | RHODIA CHIMIE (FR) | 2000-11-02 | — | — | WO | disclosed |