SCHEMBL8027883

SCHEMBL8027883

CCCC[C@H]1CC[C@H](C2CCC(c3ccc(Cl)cc3)CC2)CC1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.50
CYP2C9 P11712 1/20 0.46
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
ESR2 Q92731 2/20 0.41
SLC6A3 Q01959 1/20 0.40
SPHK1 Q9NYA1 2/20 0.40
CYP1A2 P05177 1/20 0.39
LSS P48449 1/20 0.38
IDO1 P14902 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8027889 1.00 DRD2 (0.50) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7917409 1.00 DRD2 (0.50) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8031229 0.95 DRD2 (0.49) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8031224 0.95 DRD2 (0.49) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7505169 0.95 DRD2 (0.49) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8997297 0.95 DRD2 (0.54) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8997300 0.95 DRD2 (0.54) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL10778833 0.94 DRD2 (0.48) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL10601481 0.94 DRD2 (0.48) DRD2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL10601477 0.94 DRD2 (0.48) DRD2CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0704512-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-04-03 EP disclosed
US-4405488-A LOW VISCOSITY, HIGH TRANSPARENT POINT CHISSO CORPORATION (JP) 1983-09-20 US disclosed