Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028235 | 0.85 | HTR6 (0.89) | HTR6RXFP1MAPT | |
| SCHEMBL15287801 | 0.85 | HTR6 (0.64) | HTR6RXFP1MAPT | |
| SCHEMBL8030932 | 0.83 | RXFP1 (0.79) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL4355492 | 0.81 | RXFP1 (1.00) | HTR6RXFP1MAPT | |
| SCHEMBL8016803 | 0.79 | HTR6 (0.83) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8029076 | 0.79 | HTR6 (1.00) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL15287867 | 0.77 | HTR6 (1.00) | HTR6RXFP1MAPT | |
| SCHEMBL16507160 | 0.77 | HTR6 (0.63) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL15287900 | 0.77 | HTR6 (0.57) | HTR6RXFP1MAPT | |
| SCHEMBL8032618 | 0.77 | HTR6 (0.88) | HTR6RXFP1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093934-A2 | SUBSTITUTED 3-SULPHONYL-[1,2,3]TRIAZOLO [1,5-A]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, MEDICINAL SUBSTANCE, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION AND METHODS FOR THE PRODUCTION THEREOF | ALLA CHEM, LLC (US) | 2009-07-30 | — | — | WO | disclosed |