Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028007 | 1.00 | PARP10 (0.38) | PARP10PARP15ACACBSCN9APDE4A | |
| SCHEMBL8024655 | 0.97 | ACACB (0.36) | PARP10PARP15ACACBSCN9APDE4A | |
| SCHEMBL8024653 | 0.97 | ACACB (0.36) | PARP10PARP15ACACBSCN9APDE4A | |
| SCHEMBL8028056 | 0.96 | ACACB (0.36) | PARP10PARP15ACACBSCN9ANPC1 | |
| SCHEMBL8028059 | 0.96 | ACACB (0.36) | PARP10PARP15ACACBSCN9ANPC1 | |
| SCHEMBL8022517 | 0.94 | ACACB (0.38) | PARP10PARP15ACACBSCN9APARP2 | |
| SCHEMBL8022521 | 0.94 | ACACB (0.38) | PARP10PARP15ACACBSCN9APARP2 | |
| SCHEMBL8026098 | 0.90 | PARP10 (0.35) | PARP10PARP15ACACBSCN9APDE4A | |
| SCHEMBL8013912 | 0.89 | PARP10 (0.43) | PARP10PARP15PARP2NPC1 | |
| SCHEMBL8013915 | 0.89 | PARP10 (0.43) | PARP10PARP15PARP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149990-A | Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same | CHISSO CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0884302-A1 | CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1998-12-16 | — | — | EP | disclosed |