Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073804 | 0.89 | CRBN (0.42) | CRBNLMNAMMP1MMP2MMP3 | |
| SCHEMBL3721204 | 0.75 | CRBN (0.42) | CRBNLMNACA2CA9POLB | |
| SCHEMBL653996 | 0.72 | CRBN (0.53) | CRBNLMNACA2CA9POLB | |
| SCHEMBL3072532 | 0.71 | ALDH1A1 (0.47) | CRBNLMNACA12CA1CA2 | |
| SCHEMBL2947954 | 0.71 | CRBN (0.39) | CRBNLMNAMMP1MMP2MMP3 | |
| SCHEMBL27706268 | 0.70 | CRBN (0.37) | CRBNCA12CA1CA2CA9 | |
| SCHEMBL29509217 | 0.69 | CRBN (0.50) | CRBNLMNACA2CA9POLB | |
| SCHEMBL27715006 | 0.69 | TSHR (0.53) | CRBNLMNACA2CA9POLB | |
| SCHEMBL29509273 | 0.69 | CRBN (0.50) | CRBNLMNACA2CA9POLB | |
| SCHEMBL27905681 | 0.69 | CRBN (0.50) | CRBNLMNACA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766418-B1 | VULCANISABLE COMPOUNDS ON THE BASIS OF NITRILE RUBBERS CONTAINING EPOXY GROUPS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |
| US-9725547-B2 | Vulcanisable compositions based on epoxy group-containing nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| EP-2766422-B1 | VULCANISABLE COMPOUNDS ON THE BASIS OF NITRILE RUBBERS CONTAINING EPOXY GROUPS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-05-03 | — | — | EP | disclosed |
| CN-104024318-B | Curable compositions based on the nitrile rubber containing epoxide group | 朗盛德国有限责任公司 | 2016-10-26 | — | — | CN | disclosed |
| US-20140378618-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2014-12-25 | — | — | US | disclosed |
| US-20140256886-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| CN-104024318-A | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH | 2014-09-03 | — | — | CN | disclosed |
| EP-2766422-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | LANXESS Deutschland GmbH (DE) | 2014-08-20 | — | — | EP | disclosed |
| EP-2766418-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | LANXESS Deutschland GmbH (DE) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053761-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-04-18 | — | — | WO | disclosed |
| US-5334666-A | Vulcanizable elastomer composition comprising epoxy group-containing elastomer, organic compound having at least two -C(X)-NH-C(Y)-bonds (X=O or S, Y=O or S), quaternary ammonium or phosphonium salt, and optionally a urea or thiourea compound | NIPPON ZEON CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0257640-B1 | Vulcanizable elastomer composition | NIPPON ZEON CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5292825-A | Imide or thioimide compound, and phosphine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0480770-A2 | Thermoplastic elastomer composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0480769-A2 | Method for producing impact-resistant polyester resin compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-5039756-A | Vulcanization Systems | SUMITOMO CHEMICAL CO., LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0416885-A1 | Vulcanizable epoxy group-containing elastomer composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |
| EP-0400890-A2 | Method for producing thermoplastic elastomer composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-12-05 | — | — | EP | disclosed |
| EP-0351091-A2 | Vulcanizable epoxy group-containing elastomer compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-01-17 | — | — | EP | disclosed |
| EP-0257640-A2 | Vulcanizable elastomer composition | NIPPON ZEON CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |