Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657079 | 0.90 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7661298 | 0.85 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7661372 | 0.85 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7657065 | 0.80 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7657048 | 0.80 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7659042 | 0.76 | CNR2 (0.53) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7663003 | 0.76 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7663114 | 0.76 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7658971 | 0.76 | CNR2 (0.53) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7659541 | 0.76 | MAPT (0.54) | LMNASMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |