Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 19/20 | 0.62 |
| ▸ | RARA | P10276 | 19/20 | 0.62 |
| ▸ | RARG | P13631 | 18/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12365355 | 0.93 | RARB (0.67) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8026107 | 0.89 | RARB (0.60) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7800412 | 0.87 | RARA (0.58) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8026108 | 0.87 | RARA (0.80) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL27462421 | 0.85 | RARA (0.72) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7809402 | 0.83 | RARB (0.53) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8771650 | 0.83 | RARB (0.77) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8026706 | 0.82 | CYP3A4 (0.42) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8771964 | 0.82 | RARB (0.68) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8842937 | 0.81 | RARA (0.64) | RARBRARARARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |