Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028317 | 1.00 | ESR2 (0.50) | ESR2GAAMAPTSLC18A3SIGMAR1 | |
| SCHEMBL76840 | 0.87 | ESR2 (0.63) | ESR2GAAMAPTSLC18A3SIGMAR1 | |
| Water SCHEMBL27808263 | 0.85 | ESR2 (0.61) | ESR2GAAMAPTSLC18A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9482318 | 0.83 | ESR2 (0.59) | ESR2GAAMAPTSLC18A3SIGMAR1 | |
| SCHEMBL18251909 | 0.81 | ESR2 (0.52) | ESR2MAPTSLC18A3KMT2ASMN1; SMN2 | |
| SCHEMBL8038502 | 0.81 | ESR2 (0.52) | ESR2MAPTSLC18A3SRD5A1CYP2D6 | |
| SCHEMBL8038498 | 0.81 | ESR2 (0.52) | ESR2MAPTSLC18A3SRD5A1CYP2D6 | |
| SCHEMBL10835281 | 0.80 | GAA (0.46) | ESR2GAAMAPTSLC18A3SIGMAR1 | |
| SCHEMBL11031018 | 0.80 | GAA (0.46) | ESR2GAAMAPTSLC18A3SIGMAR1 | |
| SCHEMBL8069807 | 0.80 | GAA (0.46) | ESR2GAAMAPTSLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987238-A1 | LIQUID-CRYSTALLINE COMPOUNDS HAVING BICYCLO 1.1.1]PENTANE STRUCTURE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-03-22 | — | — | EP | disclosed |