Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27808263 | 0.98 | ESR2 (0.61) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| Hydrochloric Acid SCHEMBL9482318 | 0.96 | ESR2 (0.59) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL1074881 | 0.92 | ESR2 (0.68) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL14403055 | 0.87 | ESR2 (0.78) | ESR2GAAMAPTSRD5A1 | |
| SCHEMBL10726213 | 0.87 | ESR2 (0.60) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL8028320 | 0.87 | ESR2 (0.50) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL8028317 | 0.87 | ESR2 (0.50) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL4864740 | 0.86 | GAA (0.63) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL568689 | 0.86 | GAA (0.63) | ESR2GAAMAPTSRD5A1SLC18A3 | |
| SCHEMBL4878591 | 0.86 | GAA (0.63) | ESR2GAAMAPTSRD5A1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119409615-A | 2- (Indol-3-yl) phenol compound and synthesis method thereof | 湘潭大学 | 2025-02-11 | — | — | CN | claimed |
| CN-118439921-A | Preparation method of trans-1-bromo-4- [4- (trifluoroalkyl) cyclohexyl ] benzene compound | 陕西莱特光电材料股份有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-118026995-A | Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | claimed |
| CN-117126178-A | Bisphenol thiazide compound and synthesis method thereof | 湘潭大学 | 2023-11-28 | — | — | CN | claimed |
| CN-109678788-B | 1, 2-diaryl indole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-107619386-B | Aromatic ring [ c ] carbazole derivative and synthesis method thereof | 湘潭大学 | 2020-10-13 | — | — | CN | claimed |
| CN-107417705-B | Imidazo [2,1-b] benzothiazole compound and its synthetic method | 湘潭大学 | 2019-07-02 | — | — | CN | claimed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | claimed |
| CN-108840824-A | The preparation process of 4- phenyl cycloheptylamine | 遵义医学院附属医院 | 2018-11-20 | — | — | CN | claimed |
| CN-104177298-B | Bis- substitution -4,5- dihydros -1H of 4,4--imidazoles -5- ketone, derivative and its synthetic method | 湘潭大学 | 2018-10-02 | — | — | CN | claimed |
| EP-2895442-A1 | PROCESS FOR PRODUCING PHENOL AND/OR CYCLOHEXANONE FROM CYCLOHEXYLBENZENE | ExxonMobil Chemical Patents Inc. (US) | 2015-07-22 | — | — | EP | claimed |
| CN-104640827-A | Process for producing phenol and/or cyclohexanone from cyclohexylbenzene | EXXONMOBIL CHEM PATENTS INC | 2015-05-20 | — | — | CN | claimed |
| CN-104387407-A | 6-methyl-6H-benzo[4, 5]thiophene[2, 3-b]indole and derivatives thereof as well as synthesis method of 6-methyl-6H-benzo[4, 5]thiophene[2, 3-b]indole and derivatives thereof | UNIV XIANGTAN | 2015-03-04 | — | — | CN | claimed |
| WO-2014088842-A1 | PROCESS FOR PRODUCING PHENOL | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-06-12 | — | — | WO | claimed |
| WO-2014043188-A1 | PROCESS FOR PRODUCING PHENOL AND/OR CYCLOHEXANONE FROM CYCLOHEXYLBENZENE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-03-20 | — | — | WO | claimed |
| US-20040053991-A1 | Substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof | COUNCIL SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-03-18 | — | — | US | claimed |
| WO-2003082852-A1 | NOVEL SUBSTITUTED 1,2,4-TRIOXANES USEFUL AS ANTIMALARIAL AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-09 | — | — | WO | claimed |
| WO-1998015522-A2 | METHOD FOR PREPARING TRANS-4-(4-AMINOMETHYLPHENYL) CYCLOHEXANOL DERIVATIVES | SYNTHELABO (FR) | 1998-04-16 | — | — | WO | claimed |
| US-4609677-A | 1-PHENYL-1-CYCLOHEXENE AND 4-PHENYLCYCLOHEXANONE | WARNER-LAMBERT COMPANY (US) | 1986-09-02 | — | — | US | claimed |
| US-4578405-A | 1-PHENYLCYCLOHEXENE, 4-PHENYLCYCLOHEXANONE | WARNER-LAMBERT COMPANY (US) | 1986-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053991-A1 | Substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof | DHPS, TBXAS1, ABCC1 | ESR2 3683/4885GAA 4291/4885MAPT 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.