Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748056 | 1.00 | PDE2A (0.36) | PDE2AEPHX2TUBB1ALDH1A1MAPT | |
| SCHEMBL8748052 | 1.00 | PDE2A (0.36) | PDE2AEPHX2TUBB1ALDH1A1MAPT | |
| SCHEMBL8834216 | 0.83 | RECQL (0.31) | TUBB1 | |
| SCHEMBL8834209 | 0.83 | RECQL (0.31) | TUBB1 | |
| SCHEMBL8834222 | 0.83 | RECQL (0.31) | TUBB1 | |
| SCHEMBL1509995 | 0.83 | TUBB1 (0.44) | TUBB1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL1509998 | 0.83 | TUBB1 (0.44) | TUBB1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL8745389 | 0.82 | EPHX2 (0.35) | PDE2AEPHX2TUBB1ALDH1A1MAPT | |
| SCHEMBL8752961 | 0.79 | PDE2A (0.33) | PDE2AEPHX2 | |
| SCHEMBL8752966 | 0.79 | PDE2A (0.33) | PDE2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013198-A | LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY | CHISSO CORPORATION (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0761799-A1 | Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device | Chisso Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |