Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745240 | 0.93 | EPHX2 (0.35) | EPHX2TUBB1PDE2ACHRM2APP | |
| SCHEMBL9139977 | 0.93 | EPHX2 (0.34) | EPHX2TUBB1MAPTPDE2ACHRM2 | |
| SCHEMBL8745169 | 0.85 | NFE2L2 (0.39) | — | |
| SCHEMBL9137050 | 0.82 | GRIK1 (0.37) | EPHX2ALDH1A1 | |
| SCHEMBL8748056 | 0.82 | PDE2A (0.36) | EPHX2TUBB1ALDH1A1MAPTHTT | |
| SCHEMBL8748052 | 0.82 | PDE2A (0.36) | EPHX2TUBB1ALDH1A1MAPTHTT | |
| SCHEMBL8028330 | 0.82 | PDE2A (0.36) | EPHX2TUBB1ALDH1A1MAPTHTT | |
| SCHEMBL8745628 | 0.81 | NFE2L2 (0.41) | ALDH1A1MAPTHTT | |
| SCHEMBL8745214 | 0.80 | TLR4 (0.32) | TUBB1 | |
| SCHEMBL8747225 | 0.79 | AR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |