Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016214 | 0.96 | LMNA (0.47) | PAX8POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8032038 | 0.86 | F2 (0.46) | LMNASMN1; SMN2TP53HTTF2 | |
| SCHEMBL8032566 | 0.86 | F2 (0.46) | LMNASMN1; SMN2TP53HTTF2 | |
| SCHEMBL8033092 | 0.85 | F2 (0.51) | LMNAF2 | |
| SCHEMBL8028568 | 0.82 | F2 (0.61) | PAX8POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8028095 | 0.81 | F2 (0.48) | LMNASMN1; SMN2TP53HTTNPSR1 | |
| SCHEMBL8031600 | 0.81 | BCHE (0.45) | PAX8POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8015857 | 0.81 | BRD4 (0.46) | PAX8POLBLMNAALDH1A1THRB | |
| SCHEMBL8026892 | 0.77 | F2 (0.53) | PAX8POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8032153 | 0.77 | F2 (0.55) | PAX8POLBLMNASMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |