SCHEMBL8028544

SCHEMBL8028544

CP(=O)(O)OCCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
SAT1 P21673 1/20 0.41
LMNA P02545 3/20 0.39
SLC22A6 Q4U2R8 2/20 0.39
GGH Q92820 1/20 0.38
TSHR P16473 6/20 0.38
NFKB1 P19838 1/20 0.38
PMP22 Q01453 1/20 0.38
AKR1B1 P15121 1/20 0.37
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
FFAR3 O14843 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36
PPARA Q07869 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19973408 0.85 ALDH1A1 (0.63) ALDH1A1SAT1LMNASLC22A6TSHR
SCHEMBL1877200 0.83 ALDH1A1 (0.43) ALDH1A1LMNASLC22A6GGHTSHR
SCHEMBL27692979 0.83 ALDH1A1 (0.43) ALDH1A1LMNASLC22A6GGHTSHR
SCHEMBL8649476 0.82 SAT1 (0.39) ALDH1A1SAT1EGLN1OR51E2
SCHEMBL2710223 0.80 LPAR3 (0.43) ALDH1A1LMNASLC22A6TSHRALKBH5
SCHEMBL29172121 0.79 SAT1 (0.40) ALDH1A1SAT1TSHR
SCHEMBL18686710 0.79 SAT1 (0.50) SAT1TSHRPPARDTDP1HSD17B10
SCHEMBL27566719 0.78 LPAR3 (0.41) ALDH1A1LMNATSHRALKBH5SUCNR1
Hydrochloric Acid SCHEMBL22189200 0.78 LPAR3 (0.41) ALDH1A1LMNATSHRALKBH5SUCNR1
SCHEMBL2403438 0.77 ALDH1A1 (0.39) ALDH1A1LMNASLC22A6GGHTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108939690-B High-grade fireproof flame-retardant filter cotton for high-speed motor train unit and preparation method thereof 河南省安克林滤业有限公司 2021-07-09 CN disclosed
CN-106810820-B Thermosetting alkyl polyol glycidyl ether resin composition and application thereof 广东生益科技股份有限公司 2020-07-28 CN disclosed
CN-106810820-A A kind of thermosetting alkyl polyols glycidyl ether resin composition and its application 广东生益科技股份有限公司 2017-06-09 CN disclosed
CN-104245838-B A kind of polyester hollow molded body and make the body formed method of polyester hollow molding 东洋纺株式会社 2016-08-17 CN disclosed
CN-101278081-B Method for producing sea-island type composite spun fiber TEIJIN FIBERS LTD 2014-11-26 CN disclosed
US-20140142044-A1 PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE The United States of America, as represented by the Secretary, Department of Health & Human Servic (US) 2014-05-22 US disclosed
CN-103242115-A Water gel and ammonium nitrate fuel oil explosive and production method thereof SHANDONG SHENGSHIDA CHEMICAL ENGINEERING CO LTD 2013-08-14 CN disclosed
CN-101104963-B Phosphor series polyester flame-proof fiber and producing method TORAY FIBER RES INST CN CO LTD 2011-04-20 CN disclosed
CN-101278081-A Method for producing sea-island type composite spun fiber TEIJIN FIBERS LTD (JP) 2008-10-01 CN disclosed
CN-101104963-A Phosphor series polyester flame-proof fiber and producing method TORAY FIBER RES INST CN CO LTD (CN) 2008-01-16 CN disclosed
US-6133404-A CONDENSATION POLYMERIZATION OF DIACID AND DIOL MONOMERS USING CATALYST MIXTURE COMPRISING COMPOUNDS OF TITANIUM, ZINC, ANTIMONY AND PHOSPHORUS TO FORM BIODEGRADABLE HIGH-MOLECULAR WEIGHT POLYESTER WITH GOOD THERMAL AND MECHANICAL PROPERTIES NATIONAL INSTITUTE OF TECHNOLOGY AND QUALITY (KR) 2000-10-17 US disclosed
CN-1205750-A Thermoplastic three-dimensional fiber network HOECHST CELANESE CORP (US) 1999-01-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142044-A1 PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE PLK1, PLK4, PLK3 ALDH1A1 4542/4885SAT1 4552/4885LMNA 2211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.