Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.58 |
| ▸ | ACE | P12821 | 10/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.49 |
| ▸ | CPA1 | P15085 | 7/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028768 | 1.00 | MME (0.58) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL27446786 | 0.94 | ACE (0.51) | MMEACE | |
| SCHEMBL8028778 | 0.92 | MME (0.52) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL8027428 | 0.88 | ACE (0.47) | MMEACEITGB3ITGAVITGB1 | |
| SCHEMBL8027310 | 0.88 | MME (0.72) | MMEACEACE2CPA1 | |
| SCHEMBL8027314 | 0.88 | MME (0.72) | MMEACEACE2CPA1 | |
| SCHEMBL8017382 | 0.88 | MME (0.63) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8017386 | 0.88 | MME (0.63) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8017170 | 0.87 | MME (0.61) | MMEACEACE2CPA1 | |
| SCHEMBL8017182 | 0.87 | MME (0.59) | MMEACEACE2CPA1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |