Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.47 |
| ▸ | MME | P08473 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543291 | 0.95 | PPARG (0.45) | ACEMMEPPARGPPARA | |
| SCHEMBL8029454 | 0.91 | ACE (0.57) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8027409 | 0.90 | ACE (0.52) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8027402 | 0.89 | ACE (0.48) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL27463258 | 0.89 | MME (0.64) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8030383 | 0.89 | MME (0.64) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8028768 | 0.88 | MME (0.58) | ACEMMEPPARGITGB3ITGAV | |
| SCHEMBL8028772 | 0.88 | MME (0.58) | ACEMMEPPARGITGB3ITGAV | |
| SCHEMBL8029478 | 0.87 | MME (0.59) | ACEMMEMEN1KMT2A | |
| SCHEMBL27462305 | 0.85 | ACE (0.47) | ACEMMEPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |