SCHEMBL8028850

SCHEMBL8028850

CCCCCC(CO)(CCC)C(O)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
GGPS1 O95749 2/20 0.31
FDPS P14324 1/20 0.31
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8030672 0.98 GGPS1 (0.33) GGPS1FDPSLMNAALDH1A1HSD17B10
SCHEMBL8029079 0.94 SMN1; SMN2 (0.32) SMN1; SMN2GGPS1FDPSLMNAALDH1A1
SCHEMBL8031716 0.94 TSHR (0.30) TSHR
SCHEMBL8030677 0.94 LMNA (0.36) GGPS1FDPSLMNAALDH1A1HSD17B10
SCHEMBL8034767 0.94 LMNA (0.36) GGPS1FDPSLMNAALDH1A1HSD17B10
SCHEMBL8030676 0.92 LMNA (0.34) GGPS1FDPSLMNAALDH1A1HSD17B10
SCHEMBL8019395 0.90 TSHR (0.32) ALDH1A1TSHR
SCHEMBL8032307 0.90 TSHR (0.35) TSHR
SCHEMBL8034775 0.89 SMN1; SMN2 (0.31) SMN1; SMN2GGPS1FDPSLMNAALDH1A1
SCHEMBL8029127 0.87 GGPS1 (0.33) GGPS1FDPSLMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635512-B1 Cyclic phosphites as polymer stabilizers GEN ELECTRIC (US) 2000-03-01 EP disclosed
US-5464889-A Stabilization of thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1995-11-07 US disclosed
EP-0635512-A1 Cyclic phosphites as polymer stabilizers GENERAL ELECTRIC COMPANY (US) 1995-01-25 EP disclosed