Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17837174 | 0.81 | KMT2A (0.54) | KMT2AMEN1DDB1CRBNEPHX2 | |
| SCHEMBL17055358 | 0.77 | KMT2A (0.53) | KMT2AMEN1DDB1CRBNEPHX2 | |
| SCHEMBL2628901 | 0.75 | KMT2A (0.48) | KMT2AMEN1DDB1CRBNEPHX2 | |
| SCHEMBL20714376 | 0.73 | KMT2A (0.52) | KMT2AMEN1DDB1CRBNEPHX2 | |
| SCHEMBL16400948 | 0.70 | KMT2A (0.46) | KMT2AMEN1DDB1CRBNEPHX2 | |
| SCHEMBL16401189 | 0.70 | KMT2A (0.46) | KMT2AMEN1DDB1CRBNL3MBTL1 | |
| SCHEMBL16400865 | 0.69 | KMT2A (0.45) | KMT2AMEN1DDB1CRBNEPHX2 | |
| SCHEMBL18569534 | 0.69 | KMT2A (0.44) | KMT2AMEN1DDB1CRBNL3MBTL1 | |
| SCHEMBL8589413 | 0.69 | L3MBTL1 (0.36) | KMT2AMEN1DDB1CRBNL3MBTL1 | |
| SCHEMBL22394885 | 0.68 | KMT2A (0.61) | KMT2AMEN1DDB1CRBNEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011154-A | Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present | SANOFI (FR) | 2000-01-04 | — | — | US | disclosed |