SCHEMBL8028883

SCHEMBL8028883

CCN(CC)S(=O)(=O)N(C)SBr

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8039435 0.76 CA1 (0.33) CA1LMNAHTTSMN1; SMN2
SCHEMBL8040629 0.74
SCHEMBL381097 0.73 CA1 (0.56) CA1LMNAHTTSMN1; SMN2
SCHEMBL8042374 0.72
SCHEMBL14450355 0.71 CA1 (0.41) CA1LMNAHTTSMN1; SMN2
SCHEMBL8045798 0.66
Bicarbonate SCHEMBL4462088 0.64 CA1 (0.46) CA1LMNAHTTSMN1; SMN2
SCHEMBL667530 0.60 CA1 (0.47) CA1LMNAHTTSMN1; SMN2
SCHEMBL11707030 0.60 CA1 (0.35) CA1
SCHEMBL244840 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0989171-A1 N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-03-29 EP disclosed
EP-0733651-B1 Process for preparation of N-halothiosulfonamide modified terpolymers GOODYEAR TIRE & RUBBER (US) 1999-09-01 EP disclosed
US-5756590-A MIXING TERPOLYMER WITH HALOTHIOSULFONAMIDE AND INCLUDING A HYDROHALIC ACID ACCEPTOR; OZONE RESISTANT TIRE SIDEWALLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-05-26 US disclosed
EP-0733651-A1 Process for preparation of N-halothiosulfonamide modified terpolymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-25 EP disclosed