SCHEMBL8039435

SCHEMBL8039435

CCN(CC)S(=O)(=O)N(C)SCl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8028883 0.76 CA1 (0.33) CA1LMNAHTTSMN1; SMN2
SCHEMBL8038708 0.74
SCHEMBL381097 0.73 CA1 (0.56) CA1MAPTLMNAHTTSMN1; SMN2
SCHEMBL8028849 0.72
SCHEMBL14450355 0.71 CA1 (0.41) CA1MAPTLMNAHTTSMN1; SMN2
SCHEMBL8039422 0.66
SCHEMBL9066631 0.65
SCHEMBL11206855 0.65
Bicarbonate SCHEMBL4462088 0.64 CA1 (0.46) CA1MAPTLMNAHTTSMN1; SMN2
SCHEMBL991580 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377552-B1 PROCESS FOR SYNTHESIZING N-CHLOROTHIO-SULFONAMIDES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-07-28 EP claimed
US-4992583-A Reacting n,n'-dithiobis (sulfonamide) with chlorine gas or sulfuryl chloride THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-02-12 US claimed
US-4956420-A USING A COPPER, ANTIMONY, BISMITH OR TIN SALT OF AN ORGANIC MONO-OR POLYCARBOXYLIC ACID EXXON CHEMICAL PATENTS INC. (US) 1990-09-11 US claimed
EP-0377552-A1 Process for synthesizing N-chlorothio-sulfonamides THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-07-11 EP claimed
EP-0989171-A1 N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-03-29 EP disclosed
EP-0733651-B1 Process for preparation of N-halothiosulfonamide modified terpolymers GOODYEAR TIRE & RUBBER (US) 1999-09-01 EP disclosed
US-5756590-A MIXING TERPOLYMER WITH HALOTHIOSULFONAMIDE AND INCLUDING A HYDROHALIC ACID ACCEPTOR; OZONE RESISTANT TIRE SIDEWALLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-05-26 US disclosed
EP-0733651-A1 Process for preparation of N-halothiosulfonamide modified terpolymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-25 EP disclosed
EP-0324312-B1 Polymer alloy GOODYEAR TIRE & RUBBER (US) 1995-05-24 EP disclosed
EP-0377552-B1 PROCESS FOR SYNTHESIZING N-CHLOROTHIO-SULFONAMIDES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-07-28 EP disclosed
US-4992583-A Reacting n,n'-dithiobis (sulfonamide) with chlorine gas or sulfuryl chloride THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-02-12 US disclosed
US-4956420-A USING A COPPER, ANTIMONY, BISMITH OR TIN SALT OF AN ORGANIC MONO-OR POLYCARBOXYLIC ACID EXXON CHEMICAL PATENTS INC. (US) 1990-09-11 US disclosed
EP-0377552-A1 Process for synthesizing N-chlorothio-sulfonamides THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-07-11 EP disclosed
US-4804028-A Non-staining vulcanized elastomeric composition and tires having sidewalls comprising said composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-02-14 US disclosed
US-3970133-A Chlorothio-sulfonamide-modified rubbery terpolymers and their blends THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-07-20 US disclosed