Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.66 |
| ▸ | PNMT | P11086 | 3/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692527 | 1.00 | SLC6A2 (0.66) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL268275 | 1.00 | SLC6A2 (0.66) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| Hydrochloric Acid SCHEMBL30559556 | 0.98 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| Methane SCHEMBL20481902 | 0.98 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| Hydrochloric Acid SCHEMBL3279906 | 0.98 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL2857779 | 0.84 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4TAAR1MAOA | |
| SCHEMBL17407624 | 0.83 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL3885817 | 0.83 | PNMT (0.57) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL13692532 | 0.83 | PNMT (0.57) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL196980 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115975968-B | Amine dehydrogenase mutant and application thereof in chiral amine synthesis | 中国科学院天津工业生物技术研究所 | 2024-08-02 | — | — | CN | disclosed |
| CN-115975968-A | Amine dehydrogenase mutant and application thereof in chiral amine synthesis | 中国科学院天津工业生物技术研究所 | 2023-04-18 | — | — | CN | disclosed |
| US-10000555-B2 | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | SEATTLE GENETICS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-8343928-B2 | Monomethylvaline compounds having phenylalanine side-chain replacements at the C-terminus | SEATTLE GENETICS, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| EP-0977572-A1 | USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING EATING DISORDERS | MERCK SHARP & DOHME LTD. (GB) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047513-A1 | USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING EATING DISORDERS | MERCK SHARP & DOHME LIMITED (GB) | 1998-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | SLC6A2 3436/4885SLC6A3 3411/4885SLC6A4 3408/4885 |
| US-10000555-B2 | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | PTMS, MMAB, DNPEP | SLC6A2 3422/4885SLC6A3 3352/4885SLC6A4 3371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.