Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462301 | 0.85 | CYSLTR1 (0.44) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL8032722 | 0.78 | CYSLTR1 (0.49) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL9139894 | 0.72 | PDE10A (0.53) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL8462399 | 0.72 | PDE10A (0.44) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL8462384 | 0.72 | CYSLTR1 (0.44) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL8461158 | 0.69 | CYSLTR1 (0.49) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8461147 | 0.69 | CYSLTR1 (0.49) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8461154 | 0.69 | CYSLTR1 (0.49) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8029124 | 0.68 | GPBAR1 (0.49) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL8032678 | 0.68 | GPBAR1 (0.49) | ALOX5CYSLTR1CYSLTR2GPBAR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166031-A | Substituted tetralins, chromans and related compounds in the treatment of asthma | PFIZER INC, (US) | 2000-12-26 | — | — | US | disclosed |