Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032596 | 0.87 | CCR6 (0.64) | CCR6PAX8TGM2HTTKEAP1 | |
| SCHEMBL9766156 | 0.86 | HTT (0.69) | CCR6PAX8TGM2HTTKEAP1 | |
| SCHEMBL17787485 | 0.86 | HTT (0.58) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL3309927 | 0.85 | HTT (0.67) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL917878 | 0.85 | HTT (0.67) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL10025427 | 0.85 | CCR6 (0.58) | CCR6PAX8TGM2HTTKEAP1 | |
| SCHEMBL6559526 | 0.85 | CCR6 (0.53) | CCR6PAX8TGM2HTTKEAP1 | |
| SCHEMBL415526 | 0.85 | CCR6 (0.60) | CCR6PAX8TGM2HTTKEAP1 | |
| SCHEMBL2075425 | 0.85 | CCR6 (0.60) | CCR6PAX8TGM2HTTKEAP1 | |
| SCHEMBL411758 | 0.85 | CCR6 (0.60) | CCR6PAX8TGM2HTTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |