Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27464982 | 0.91 | LMNA (0.52) | CCR6PAX8TGM2HTTLMNA | |
| SCHEMBL13661577 | 0.86 | CCR6 (0.52) | CCR6PAX8L3MBTL1CA1CA2 | |
| SCHEMBL10954785 | 0.85 | TGM2 (0.60) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL15055271 | 0.85 | CCR6 (0.51) | CCR6PAX8TGM2LMNASMN1; SMN2 | |
| SCHEMBL8029255 | 0.85 | CCR6 (0.57) | CCR6PAX8TGM2HTTLMNA | |
| SCHEMBL13661588 | 0.85 | CCR6 (0.53) | CCR6PAX8L3MBTL1CA1CA2 | |
| SCHEMBL2453446 | 0.84 | HTT (0.60) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL15841146 | 0.84 | CCR6 (0.50) | CCR6PAX8TGM2LMNAL3MBTL1 | |
| SCHEMBL8032596 | 0.83 | CCR6 (0.64) | CCR6PAX8TGM2HTTLMNA | |
| SCHEMBL3445880 | 0.83 | HTT (0.62) | TGM2HTTLMNASMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151165-C | Macrolides with anti-inflammatory activity | �ź㴫 | 2004-05-26 | — | — | CN | disclosed |
| EP-1100762-B1 | ERYTHROMYCIN DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2004-03-10 | — | — | EP | disclosed |
| EP-1100806-B1 | ERYTHROMYCIN DERIVATIVE WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2003-11-19 | — | — | EP | disclosed |
| US-6583120-B1 | Grampositive and gramnegative bacterial growth regulators having improved efficiency, used for preventing infections in humans and as veterinary medicine | ZAMBON GROUP S.A. (IT) | 2003-06-24 | — | — | US | disclosed |
| US-6468979-B1 | ERYTHROMYCIN DERIVATIVES WITH BIHETEROCYCLIC GROUP AS SUBSTITUENT AT END OF CHAIN HAVE PARTICULARLY BROAD SPECTRUM OF ACTIVITY AND LONG DURATION OF ACTION | ZAMBON GROUP S.P.A. (IT) | 2002-10-22 | — | — | US | disclosed |
| CN-1336932-A | Macrolides with anti-inflammatory activity | ZAMBON SPA (IT) | 2002-02-20 | — | — | CN | disclosed |
| EP-1100762-A2 | ERYTHROMYCIN DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2001-05-23 | — | — | EP | disclosed |
| EP-1100806-A1 | ERYTHROMYCIN DERIVATIVE WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006586-A1 | ERYTHROMYCIN DERIVATIVE WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006606-A2 | ERYTHROMYCIN DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2000-02-10 | — | — | WO | disclosed |