Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463728 | 0.78 | CHRM5 (0.35) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL29030426 | 0.78 | CYP1A2 (0.40) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL446739 | 0.78 | CHRM5 (0.35) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL6550933 | 0.75 | — | — | |
| SCHEMBL23701256 | 0.73 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL7904556 | 0.70 | CYP1A2 (0.44) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL28585886 | 0.68 | CYP1A2 (0.42) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL11127896 | 0.67 | ADH1A (0.35) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL15091738 | 0.67 | CHRM5 (0.35) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL17138312 | 0.67 | CHRM5 (0.35) | CYP1A2ACHECHRM5ADRA2CCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1245807-A | Preparation method of silicane whose alpha-position related to silicon atom possesses tertiary alkyl radical | WACKER CHEMIE GMBH (DE) | 2000-03-01 | — | — | CN | disclosed |
| EP-0980870-A1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | Wacker-Chemie GmbH (DE) | 2000-02-23 | — | — | EP | disclosed |