Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993202 | 0.96 | HSD11B1 (0.47) | MAOBLPLLIPGCNR1CNR2 | |
| SCHEMBL8040096 | 0.92 | CNR2 (0.46) | MAOBLPLLIPGCNR2HSD11B1 | |
| SCHEMBL29732195 | 0.90 | ABL1 (0.52) | CNR1CNR2CA2ALOX5MAPT | |
| SCHEMBL15238788 | 0.87 | PPARA (0.50) | MAOBLPLLIPGHSD11B1ALOX5 | |
| SCHEMBL28829436 | 0.86 | HSD11B1 (0.56) | NISCHCA2HSD11B1 | |
| SCHEMBL30684865 | 0.86 | HSD11B1 (0.56) | NISCHCA2HSD11B1 | |
| SCHEMBL10825673 | 0.86 | GRIA4 (0.54) | MAOBNPC1MAPTRAB9A | |
| SCHEMBL28256624 | 0.86 | MAOB (0.68) | MAOBCNR2HSD11B1 | |
| SCHEMBL4453316 | 0.86 | CNR1 (0.55) | MAOBLPLLIPGCNR1CNR2 | |
| SCHEMBL9418555 | 0.84 | SMN1; SMN2 (0.42) | MAOBLPLLIPGNISCHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |