Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040927 | 0.84 | HSD17B10 (0.59) | FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8029213 | 0.84 | ACACB (0.44) | FFAR1FFAR4ACACBKCNH2 | |
| SCHEMBL8040160 | 0.84 | CYP2A6 (0.44) | CYP2A6CYP1A1CYP1A2CYP1B1FFAR1 | |
| SCHEMBL9333082 | 0.82 | CYP1A1 (0.57) | CYP2A6CYP1A1CYP1A2CYP1B1TSHR | |
| SCHEMBL9465555 | 0.80 | TSHR (0.47) | CYP2A6FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8040821 | 0.80 | HSD17B10 (0.49) | FFAR1FFAR4TSHRHSD17B10KCNH2 | |
| SCHEMBL8029405 | 0.78 | CYP2A6 (0.48) | CYP2A6CYP1A1CYP1A2CYP1B1FFAR1 | |
| SCHEMBL8029224 | 0.78 | FFAR1 (0.49) | CYP2A6FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8042641 | 0.78 | TSHR (0.42) | CYP1A1CYP1A2CYP1B1FFAR1FFAR4 | |
| SCHEMBL9509240 | 0.78 | CYP2A6 (0.56) | CYP2A6FFAR1FFAR4TAAR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| CN-1135515-A | Liquid crystal alkynyl tolane compound, liquid crystal composition and liquid crystal display part | CHISSO CORP (JP) | 1996-11-13 | — | — | CN | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |