Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369268 | 0.79 | FBP1 (0.57) | FBP1HSP90AA1HSP90AB1ADORA2AADORA2B | |
| SCHEMBL6337579 | 0.77 | FBP1 (0.50) | FBP1HSP90AA1HSP90AB1 | |
| SCHEMBL4954814 | 0.76 | FBP1 (0.49) | FBP1HSP90AA1HSP90AB1ADORA2AADORA2B | |
| SCHEMBL4954196 | 0.73 | ADORA2A (0.61) | FBP1HSP90AA1HSP90AB1ADORA2AADORA2B | |
| SCHEMBL4958943 | 0.73 | FBP1 (0.53) | FBP1HSP90AA1HSP90AB1HSPA5 | |
| SCHEMBL5373064 | 0.72 | FBP1 (0.50) | FBP1HSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL5362049 | 0.70 | FBP1 (0.36) | FBP1HSP90AA1HSP90AB1 | |
| SCHEMBL4956466 | 0.70 | FBP1 (0.64) | FBP1HSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL4956730 | 0.69 | FBP1 (0.56) | FBP1HSP90AA1HSP90AB1ADORA2AADORA2B | |
| SCHEMBL4956734 | 0.69 | FBP1 (0.53) | FBP1HSP90AA1HSP90AB1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060182-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | Metabasis Therapeutics, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045016-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |