Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757746 | 1.00 | SPHK1 (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL7757740 | 1.00 | SPHK1 (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL8029517 | 1.00 | SPHK1 (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL8030041 | 1.00 | SPHK1 (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL7757745 | 1.00 | SPHK1 (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL8440158 | 0.92 | ADRA1A (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL8440156 | 0.92 | ADRA1A (0.35) | SPHK1ADRA1AHCRTR2USP5HDAC6 | |
| SCHEMBL8084504 | 0.91 | SPHK1 (0.37) | SPHK1ADRA1AHTR2AHTR2CHTR2B | |
| SCHEMBL8398619 | 0.91 | USP5 (0.34) | ADRA1AHCRTR2USP5HDAC6HTR2A | |
| SCHEMBL8084502 | 0.91 | SPHK1 (0.37) | SPHK1ADRA1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713878-B1 | A method of manufacturing a trans silacyclohexane compound | SHINETSU CHEMICAL CO (JP) | 2000-02-16 | — | — | EP | disclosed |
| EP-0713878-A1 | A method of manufacturing a trans silacyclohexane compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1996-05-29 | — | — | EP | disclosed |