Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770984 | 0.89 | PHLPP2 (0.62) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL8059751 | 0.89 | PHLPP2 (0.62) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL28820269 | 0.85 | PHLPP2 (0.59) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL13994972 | 0.82 | PHLPP2 (0.49) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL13997541 | 0.82 | PHLPP2 (0.54) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL29723780 | 0.81 | PHLPP2 (0.53) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL20735272 | 0.80 | PHLPP2 (0.60) | PHLPP2ALDH1A1MEN1THRBKMT2A | |
| SCHEMBL10350674 | 0.79 | CD40 (0.51) | PHLPP2ALDH1A1ENPP2MPLCD40 | |
| SCHEMBL10350675 | 0.79 | CD40 (0.51) | PHLPP2ALDH1A1ENPP2MPLCD40 | |
| SCHEMBL10383549 | 0.78 | PHLPP2 (0.55) | PHLPP2ALDH1A1MEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776947-B1 | Fiber-reactive dyestuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| EP-0775732-B1 | Fiber-reactive dyestuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| EP-0776947-A1 | Fiber-reactive dyestuffs, their preparation and use | Ciba SC Holding AG (CH) | 1997-06-04 | — | — | EP | disclosed |
| EP-0775732-A1 | Fiber-reactive dyestuffs, their preparation and use | Ciba SC Holding AG (CH) | 1997-05-28 | — | — | EP | disclosed |