SCHEMBL8059751

SCHEMBL8059751

COc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(N)ccc3c2O)c(S(=O)(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.62
CD40 P25942 1/20 0.48
CD40LG P29965 1/20 0.48
ENPP2 Q13822 10/20 0.47
MPL P40238 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
MAPK1 P28482 1/20 0.41
BRCA1 P38398 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770984 1.00 PHLPP2 (0.62) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL28820269 0.96 PHLPP2 (0.59) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL13997541 0.93 PHLPP2 (0.54) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL20735272 0.90 PHLPP2 (0.60) PHLPP2CD40CD40LGENPP2MEN1
SCHEMBL29723780 0.90 PHLPP2 (0.53) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL10350674 0.89 CD40 (0.51) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL10350675 0.89 CD40 (0.51) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL8029582 0.89 PHLPP2 (0.54) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL10600174 0.89 PHLPP2 (0.60) PHLPP2CD40CD40LGENPP2MPL
SCHEMBL10383549 0.89 PHLPP2 (0.55) PHLPP2CD40CD40LGENPP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 US claimed
US-7462228-B2 Water-base black ink composition and colored product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-12-09 US disclosed
EP-1602695-B1 WATER-BASE BLACK INK COMPOSITION AND COLORED MATERIAL NIPPON KAYAKU KK (JP) 2008-04-23 EP disclosed
US-20070227388-A1 Tetrakisazo Compound, Coloring Matter for Recording, Ink Composition and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-10-04 US disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-5931975-A TRIAZINE REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US disclosed
US-5837827-A Fibre-reactive dyes, their preparation and their use CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-17 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
US-5831038-A Dig 20 halogenotriazinyl group-containing fiber reactive dyes, their preparation and their use CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-03 US disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
US-4808706-A WET- AND LIGHFAST; SOLUBLE CIBA-GEIGY CORPORATION (US) 1989-02-28 US disclosed
EP-0167219-B1 FIBER-REACTIVE COMPOUND HAVING BOTH PYRIDINIOTRIAZINYL AND VINYLSULFONE TYPE GROUPS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-28 EP disclosed
US-4772323-A IMPROVED STORAGE AND EJECTION STABILITY CANON KABUSHIKI KAISHA (JP) 1988-09-20 US disclosed
US-4758658-A Water-soluble formazan dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-19 US disclosed
EP-0219232-A2 Water-soluble dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-22 EP disclosed
US-4626589-A Organic dye compound having both pyridiniotriazinyl and vinylsulfone type fiber-reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-02 US disclosed
EP-0167219-A1 Fiber-reactive compound having both pyridiniotriazinyl and vinylsulfone type groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-08 EP disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed
US-4263206-A Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-04-21 US disclosed
US-4213899-A FOR CELLULOSE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-22 US disclosed