Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031216 | 0.89 | KCNN4 (0.38) | KCNN4ALDH1A1HPGDSMN1; SMN2HTR7 | |
| SCHEMBL8029354 | 0.89 | KCNN4 (0.38) | KCNN4ALDH1A1HPGDSMN1; SMN2HTR7 | |
| SCHEMBL14996192 | 0.89 | KCNN4 (0.43) | KCNN4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL13002561 | 0.85 | KCNN4 (0.38) | KCNN4ALDH1A1HTR7DHODHMEN1 | |
| SCHEMBL8031257 | 0.85 | KCNN4 (0.41) | KCNN4ALDH1A1HPGDSMN1; SMN2HTR7 | |
| SCHEMBL13059500 | 0.83 | DHODH (0.33) | SMN1; SMN2DHODHMAPTRAB9A | |
| SCHEMBL8033819 | 0.83 | NPC1 (0.42) | SMN1; SMN2DHODHMAPTRAB9ADPP4 | |
| SCHEMBL8031252 | 0.82 | POLB (0.40) | ALDH1A1SMN1; SMN2PDE10ADHODHMAPT | |
| SCHEMBL8033068 | 0.80 | NPC1 (0.37) | DHODHRAB9ADPP4 | |
| SCHEMBL14996191 | 0.78 | KCNN4 (0.41) | KCNN4PDE10AMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250157-B1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC LTD (IN) | 2014-11-05 | — | — | EP | disclosed |
| WO-2009093269-A1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC LIMITED (IN) | 2009-07-30 | — | — | WO | disclosed |